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Rytkin E., Mirzaev K.B., Smirnov V.V., Ryzhikova K.A., Sozaeva Zh.A., Andreev D.A., Sychev D.A. Assessment of CYP2C19, ABCB1, CYP3A5 Genes Polymorphisms’ and CYP3A4 Isoenzyme Activity Influence on Major Adverse Cardiovascular Events Among Patients with an Acute Coronary Syndrome Undergoing Percutaneous Coronary Intervention. Clinical Therapeutics, Vol. 39, Issue 8, e67–e68



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Sychev DA, Rozhkov AV, Ananichuk AV, Kazakov RE. Evaluation of genotype-guided acenocoumarol dosing algorithms in Russian patients. Drug Metabol Pers Ther 2017; aop. 

DOI 10.1515/dmpt-2016-0043

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Zhestovskaja AS, Kukes VG, Sychev DA. Personalized medicine: myth or reality? The position of Russian clinical pharmacologists. EPMA J.2013;4(1):13.

doi: 10.1186/1878-5085-4-13

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Sychev DA, Shuev GN, Suleymanov SS, Ryzhikova KA, Mirzaev KB, Grishina EA, Snalina NE, Sozaeva ZA, Grabuzdov AM, Matsneva IA. Comparison of CYP2C9, CYP2C19, CYP2D6, ABCB1, and SLCO1B1 gene-polymorphism frequency in Russian and Nanai populations. Pharmgenomics Pers Med. 2017;10:93-99.

doi: 10.2147/PGPM.S129665.

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Sychev DA, Shuev GN, Chertovskih JV, Maksimova NR, Grachev AV, Syrkova OA. The frequency of SLCO1B1*5 polymorphism genotypes among Russian and Sakha (Yakutia) patients with hypercholesterolemia. Pharmgenomics Pers Med. 2016;9:59–63.

doi: 10.2147/PGPM.S99634

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  1. Zagorodnikova Goryachkina K, Burbello A, Sychev D, et al. Clinical pharmacology in Russia-historical development and current state. Eur J Clin Pharmacol. 2015;71(2):159-63.
  2. Sychev DA, Zastrozhin MS, Smirnov VV, et al. The correlation between CYP2D6 isoenzyme activity and haloperidol efficacy and safety profile in patients with alcohol addiction during the exacerbation of the addiction. Pharmgenomics Pers Med. 2016;9:89–95.
  3. Mirzaev K, Sychev D, Arutyunyan G, et al. Cytochrome 2C19 Enzyme Polymorphism Frequency in Different Indigenous Ethnic Groups in Russian Federation: A Systematic Review J Pharmacogenomics Pharmacoproteomics 2014 5:136.
  4. Zastrozhin MS, Smirnov VV, Sychev DA, et al. CYP3A4 activity and haloperidol effects in alcohol addicts. Int J Risk Saf Med. 2015;27:23-4.